Pfam Domains GO Terms
| C2 |
| insulin receptor signaling pathway via phosphatidylinositol 3-kinase |
| positive regulation of vesicle fusion |
| positive regulation of protein targeting to membrane |
| regulation of vesicle fusion |
| regulation of protein targeting to membrane |
| positive regulation of glucose import |
| positive regulation of glucose transmembrane transport |
| intracellular protein transmembrane transport |
| regulation of glucose import |
| calcium-dependent phospholipid binding |
| protein transmembrane transport |
| vesicle fusion |
| regulation of glucose transmembrane transport |
| organelle membrane fusion |
| regulation of protein targeting |
| insulin receptor signaling pathway |
| ruffle membrane |
| organelle fusion |
| positive regulation of protein localization to membrane |
| membrane fusion |
| cell cortex |
| cytoplasmic vesicle membrane |
| positive regulation of intracellular protein transport |
| microtubule organizing center |
| cellular response to insulin stimulus |
| protein localization to plasma membrane |
| regulation of protein localization to membrane |
| positive regulation of transmembrane transport |
| positive regulation of intracellular transport |
| response to insulin |
| protein localization to cell periphery |
| regulation of intracellular protein transport |
| cellular response to peptide hormone stimulus |
| vesicle organization |
| positive regulation of cellular protein localization |
| cellular response to peptide |
| regulation of intracellular transport |
| response to peptide hormone |
| positive regulation of protein transport |
| positive regulation of establishment of protein localization |
| response to peptide |
| protein localization to membrane |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| regulation of cellular protein localization |
| regulation of vesicle-mediated transport |
| regulation of transmembrane transport |
| cellular response to organonitrogen compound |
| cellular response to hormone stimulus |
| positive regulation of organelle organization |
| cellular response to nitrogen compound |
| regulation of protein transport |
| enzyme linked receptor protein signaling pathway |
| calcium ion binding |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| membrane organization |
| response to hormone |
| regulation of cellular localization |
| positive regulation of transport |
| intracellular protein transport |
| response to organonitrogen compound |
| regulation of protein localization |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| positive regulation of cellular component organization |
| cellular response to endogenous stimulus |
| transmembrane transport |
| regulation of organelle organization |
| response to endogenous stimulus |
| protein transport |
| intracellular transport |
| peptide transport |
| response to oxygen-containing compound |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| establishment of localization in cell |
| nitrogen compound transport |
| regulation of transport |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution