CDK10
Gene Information
- Official Symbol: CDK10
- Official Name: cyclin dependent kinase 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 8558
- UniProt: Q15131
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Pkinase |
| Pkinase Tyr |
GO Terms
| traversing start control point of mitotic cell cycle |
| negative regulation of cilium assembly |
| negative regulation of plasma membrane bounded cell projection assembly |
| cyclin-dependent protein serine/threonine kinase activity |
| positive regulation of G1/S transition of mitotic cell cycle |
| negative regulation of organelle assembly |
| positive regulation of cell cycle G1/S phase transition |
| positive regulation of mitotic cell cycle phase transition |
| regulation of cilium assembly |
| peptidyl-threonine phosphorylation |
| peptidyl-threonine modification |
| positive regulation of cell cycle phase transition |
| ciliary basal body |
| regulation of G1/S transition of mitotic cell cycle |
| positive regulation of mitotic cell cycle |
| regulation of cell cycle G1/S phase transition |
| negative regulation of cell projection organization |
| regulation of plasma membrane bounded cell projection assembly |
| regulation of cell projection assembly |
| regulation of organelle assembly |
| positive regulation of cell cycle process |
| regulation of actin cytoskeleton organization |
| protein serine/threonine kinase activity |
| negative regulation of organelle organization |
| positive regulation of cell cycle |
| regulation of actin filament-based process |
| regulation of mitotic cell cycle phase transition |
| regulation of cell cycle phase transition |
| regulation of cytoskeleton organization |
| positive regulation of MAPK cascade |
| regulation of mitotic cell cycle |
| negative regulation of cell population proliferation |
| regulation of plasma membrane bounded cell projection organization |
| negative regulation of cellular component organization |
| regulation of cell projection organization |
| regulation of MAPK cascade |
| regulation of cell cycle process |
| peptidyl-amino acid modification |
| regulation of cellular component biogenesis |
| protein phosphorylation |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| positive regulation of phosphorylation |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| cell projection organization |
| regulation of cell cycle |
| positive regulation of protein modification process |
| phosphorylation |
| regulation of organelle organization |
| regulation of protein phosphorylation |
| ATP binding |
| regulation of phosphorylation |
| positive regulation of cellular protein metabolic process |
| regulation of cell population proliferation |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 2602
- Expression level (log2 read counts): 6.43
Expression Distribution
CDK10 Expression in NALM6 Cells: 6.43
