UniProt Summary: Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
SH3 2
SH3 1
RhoGEF
BAR
GO Terms
Golgi stack
Rho guanyl-nucleotide exchange factor activity
presynapse
regulation of Rho protein signal transduction
regulation of cell shape
cell-cell junction
regulation of Ras protein signal transduction
synapse
aging
regulation of small GTPase mediated signal transduction
cytoskeleton
regulation of cell morphogenesis
Golgi apparatus
regulation of anatomical structure morphogenesis
intracellular signal transduction
regulation of intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)