EXTL1

Gene Information

Official Symbol: EXTL1
Official Name: exostosin like glycosyltransferase 1
Aliases and Previous Symbols: N/A
Entrez ID: 2134
UniProt: Q92935
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Probable glycosyltransferase. {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Deguelin 0.05μM R02 exp69	-2.69
SB202190 10μM R03 exp148	-2.3
Talazoparib 0.006μM R06 exp299	-2.27
R-DABN 8μM R03 exp111	-1.89
BVD-523 15μM R02 exp67	-1.81
MS023 7μM R03 exp135	-1.77
S-DABN 8μM R03 exp112	-1.75
Dexamethasone 0.006μM R07 exp351	1.85
Hydroxychloroquine 30μM R08 exp490	2.03

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 2696
Expression level (log2 read counts): -2.08

Expression Distribution