FOXB1
Gene Information
- Official Symbol: FOXB1
- Official Name: forkhead box B1
- Aliases and Previous Symbols: N/A
- Entrez ID: 27023
- UniProt: Q99853
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Fork head |
GO Terms
| cell migration in diencephalon |
| mammillothalamic axonal tract development |
| mammillary body development |
| inferior colliculus development |
| corpora quadrigemina development |
| mammillary axonal complex development |
| axon target recognition |
| epithelial cell differentiation involved in mammary gland alveolus development |
| hypothalamus cell migration |
| floor plate development |
| thalamus development |
| mammary gland epithelial cell differentiation |
| mammary gland alveolus development |
| mammary gland lobule development |
| hypothalamus development |
| lactation |
| visual learning |
| visual behavior |
| telencephalon cell migration |
| mammary gland epithelium development |
| forebrain cell migration |
| somitogenesis |
| body fluid secretion |
| diencephalon development |
| associative learning |
| somite development |
| midbrain development |
| segmentation |
| spinal cord development |
| limbic system development |
| mammary gland development |
| negative regulation of neuron apoptotic process |
| learning |
| neural tube development |
| negative regulation of neuron death |
| regulation of neuron apoptotic process |
| anterior/posterior pattern specification |
| telencephalon development |
| learning or memory |
| cognition |
| response to light stimulus |
| regulation of neuron death |
| urogenital system development |
| regionalization |
| axonogenesis |
| forebrain development |
| axon development |
| gland development |
| sequence-specific DNA binding |
| cell morphogenesis involved in neuron differentiation |
| pattern specification process |
| response to radiation |
| neuron projection morphogenesis |
| plasma membrane bounded cell projection morphogenesis |
| cell projection morphogenesis |
| regulation of body fluid levels |
| cell part morphogenesis |
| cell morphogenesis involved in differentiation |
| behavior |
| chordate embryonic development |
| embryo development ending in birth or egg hatching |
| neuron projection development |
| epithelial cell differentiation |
| cell morphogenesis |
| brain development |
| head development |
| neuron development |
| cellular component morphogenesis |
| tube development |
| negative regulation of apoptotic process |
| anatomical structure formation involved in morphogenesis |
| negative regulation of programmed cell death |
| cell migration |
| embryo development |
| central nervous system development |
| negative regulation of cell death |
| neuron differentiation |
| cell motility |
| localization of cell |
| epithelium development |
| secretion |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| response to abiotic stimulus |
| locomotion |
| nervous system process |
| generation of neurons |
| regulation of apoptotic process |
| movement of cell or subcellular component |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| regulation of programmed cell death |
| neurogenesis |
| cell development |
| regulation of cell death |
| tissue development |
| system process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Nicotinamide Riboside 100μM R03 exp139 | -1.98 |
| Chloramphenicol 2μM R00 exp12 | 1.81 |
| HMS-I2 1μM R06 exp286 | 1.83 |
| Wortmannin 5μM R00 exp38 | 1.9 |
| LLY-284 2.6μM R06 exp291 | 1.93 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 2471
- Expression level (log2 read counts): -2.01
Expression Distribution
FOXB1 Expression in NALM6 Cells: -2.01
