Pfam Domains GO Terms
| G glu transpept |
| peptidyltransferase activity |
| hypoglycin A gamma-glutamyl transpeptidase activity |
| leukotriene C4 gamma-glutamyl transferase activity |
| glutathione hydrolase activity |
| leukotriene D4 metabolic process |
| glutathione catabolic process |
| leukotriene D4 biosynthetic process |
| glutathione biosynthetic process |
| nonribosomal peptide biosynthetic process |
| leukotriene biosynthetic process |
| cellular modified amino acid catabolic process |
| peptide catabolic process |
| leukotriene metabolic process |
| icosanoid biosynthetic process |
| cellular modified amino acid biosynthetic process |
| negative regulation of response to oxidative stress |
| glutathione metabolic process |
| sulfur compound catabolic process |
| cofactor catabolic process |
| regulation of response to oxidative stress |
| fatty acid derivative biosynthetic process |
| icosanoid metabolic process |
| fatty acid derivative metabolic process |
| sulfur compound biosynthetic process |
| cellular modified amino acid metabolic process |
| cofactor biosynthetic process |
| carboxylic acid biosynthetic process |
| organic acid biosynthetic process |
| sulfur compound metabolic process |
| translation |
| peptide biosynthetic process |
| cofactor metabolic process |
| drug metabolic process |
| amide biosynthetic process |
| peptide metabolic process |
| small molecule biosynthetic process |
| cellular amide metabolic process |
| carboxylic acid metabolic process |
| oxoacid metabolic process |
| organic acid metabolic process |
| organonitrogen compound catabolic process |
| proteolysis |
| organonitrogen compound biosynthetic process |
| regulation of response to stress |
| negative regulation of response to stimulus |
| cellular nitrogen compound biosynthetic process |
| cellular macromolecule biosynthetic process |
| small molecule metabolic process |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| cellular catabolic process |
| gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| THZ1 0.06μM R08 exp531 | 1.78 |
| YM155 0.001μM R08 exp432 | 2.07 |
| Benzoate 10000μM R08 exp455 | 2.22 |
| Gene | Correlation |
|---|---|
| RRM1 | 0.524 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution