Pfam Domains GO Terms
| Metallophos 2 |
| Metallophos |
| GPI anchor binding |
| phosphoric diester hydrolase activity |
| endoplasmic reticulum exit site |
| GPI anchor biosynthetic process |
| GPI anchor metabolic process |
| manganese ion binding |
| cis-Golgi network |
| glycolipid biosynthetic process |
| endoplasmic reticulum-Golgi intermediate compartment membrane |
| endoplasmic reticulum-Golgi intermediate compartment |
| protein lipidation |
| lipoprotein biosynthetic process |
| phosphatidylinositol biosynthetic process |
| glycolipid metabolic process |
| liposaccharide metabolic process |
| lipoprotein metabolic process |
| membrane lipid biosynthetic process |
| phosphatidylinositol metabolic process |
| membrane lipid metabolic process |
| glycerophospholipid biosynthetic process |
| endoplasmic reticulum to Golgi vesicle-mediated transport |
| glycerolipid biosynthetic process |
| phospholipid biosynthetic process |
| glycerophospholipid metabolic process |
| Golgi vesicle transport |
| phospholipid metabolic process |
| glycerolipid metabolic process |
| organophosphate biosynthetic process |
| lipid biosynthetic process |
| carbohydrate derivative biosynthetic process |
| organophosphate metabolic process |
| cellular lipid metabolic process |
| Golgi apparatus |
| endoplasmic reticulum |
| carbohydrate derivative metabolic process |
| lipid metabolic process |
| organonitrogen compound biosynthetic process |
| intracellular transport |
| cellular macromolecule biosynthetic process |
| macromolecule biosynthetic process |
| establishment of localization in cell |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| BH1 1μM R04 exp169 | -1.73 |
| Hydroxyurea 100μM R07 exp329 | 1.84 |
| Mubritinib 0.2μM R02 exp65 | 2.01 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution