NOL6

Gene Information

Official Symbol: NOL6
Official Name: nucleolar protein 6
Aliases and Previous Symbols: N/A
Entrez ID: 65083
UniProt: Q9H6R4
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Bortezomib 0.05μM R00 exp7	-1.84
Colchicine 0.009μM R05 exp215	1.74
GW501516 25μM R06 exp285	1.77
Arsenic trioxide 60μM R08 exp449	1.78
BI-2536 0.0042μM R03 exp95	1.83
Nicotine 3000μM R08 exp510	1.97
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	1.99
DKK1 89ng/ml R08 exp477	2.24
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	2.71

Global Fraction of Cell Lines Where Essential: 605/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	25/28
blood	25/28
bone	21/26
breast	23/33
central nervous system	44/56
cervix	4/4
colorectal	11/17
esophagus	11/13
fibroblast	0/1
gastric	15/16
kidney	20/21
liver	17/20
lung	69/75
lymphocyte	11/16
ovary	21/26
pancreas	20/24
peripheral nervous system	11/16
plasma cell	8/15
prostate	0/1
skin	21/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	14/22
urinary tract	21/29
uterus	4/5

Essentiality in NALM6

Essentiality Rank: 88
Expression level (log2 read counts): 6.82

Expression Distribution