NTNG2
Gene Information
- Official Symbol: NTNG2
- Official Name: netrin G2
- Aliases and Previous Symbols: N/A
- Entrez ID: 84628
- UniProt: Q96CW9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Laminin EGF |
| Laminin N |
GO Terms
| anchored component of presynaptic active zone membrane |
| postsynaptic specialization assembly |
| postsynaptic specialization organization |
| postsynapse assembly |
| synaptic membrane adhesion |
| motor neuron axon guidance |
| regulation of presynapse assembly |
| Flemming body |
| regulation of presynapse organization |
| anchored component of plasma membrane |
| intercellular bridge |
| Schaffer collateral - CA1 synapse |
| postsynapse organization |
| synapse assembly |
| regulation of synapse assembly |
| regulation of synapse organization |
| regulation of synapse structure or activity |
| cell-cell adhesion via plasma-membrane adhesion molecules |
| axon guidance |
| neuron projection guidance |
| synapse organization |
| axon |
| glutamatergic synapse |
| axonogenesis |
| axon development |
| cell morphogenesis involved in neuron differentiation |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| neuron projection morphogenesis |
| plasma membrane bounded cell projection morphogenesis |
| cell projection morphogenesis |
| cell-cell adhesion |
| cell part morphogenesis |
| chemotaxis |
| taxis |
| cell morphogenesis involved in differentiation |
| neuron projection development |
| cell morphogenesis |
| organelle assembly |
| molecular function |
| neuron development |
| cellular component morphogenesis |
| regulation of nervous system development |
| cell adhesion |
| biological adhesion |
| animal organ morphogenesis |
| regulation of cellular component biogenesis |
| neuron differentiation |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| locomotion |
| generation of neurons |
| movement of cell or subcellular component |
| neurogenesis |
| cell development |
| tissue development |
| extracellular region |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Alda-1 10μM R06 exp262 | -1.96 |
| Latrunculin-B 10μM R07 exp374 | -1.79 |
| Cannabidiol 20μM R08 exp466 | 1.71 |
| Milciclib 2μM R08 exp502 | 1.72 |
| DKK1 89ng/ml R08 exp477 | 1.74 |
| Torin1 0.08μM R02 exp82 | 1.87 |
| PT-1 25μM R07 exp392 | 1.95 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 10284
- Expression level (log2 read counts): 2.27
Expression Distribution
NTNG2 Expression in NALM6 Cells: 2.27
