POP4

Entrez Summary: N/A
UniProt Summary: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 22/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	1/28
bone	1/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	1/17
esophagus	1/13
fibroblast	0/1
gastric	0/16
kidney	1/21
liver	0/20
lung	3/75
lymphocyte	1/16
ovary	1/26
pancreas	0/24
peripheral nervous system	3/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	1/29
uterus	0/5

Expression Distribution