Pfam Domains GO Terms
| zf-C2H2 |
| histone H4-R3 methylation |
| histone methyltransferase binding |
| histone arginine methylation |
| peptidyl-arginine methylation |
| peptidyl-arginine modification |
| histone methyltransferase complex |
| methyltransferase activity |
| chromatin DNA binding |
| histone methylation |
| protein methylation |
| protein alkylation |
| macromolecule methylation |
| methylation |
| RNA polymerase II regulatory region sequence-specific DNA binding |
| histone modification |
| covalent chromatin modification |
| sequence-specific DNA binding |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| transcription by RNA polymerase II |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| transcription, DNA-templated |
| nucleic acid-templated transcription |
| RNA biosynthetic process |
| DNA-binding transcription factor activity |
| chromatin organization |
| peptidyl-amino acid modification |
| chromosome organization |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| positive regulation of transcription by RNA polymerase II |
| organic cyclic compound biosynthetic process |
| positive regulation of transcription, DNA-templated |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| cellular nitrogen compound biosynthetic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| RNA metabolic process |
| cellular macromolecule biosynthetic process |
| positive regulation of RNA metabolic process |
| macromolecule biosynthetic process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| RRM1 | 0.491 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution