PRPF40A
Gene Information
- Official Symbol: PRPF40A
- Official Name: pre-mRNA processing factor 40 homolog A
- Aliases and Previous Symbols: N/A
- Entrez ID: 55660
- UniProt: O75400
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. {ECO:0000250, ECO:0000269|PubMed:21834987}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1527
- Expression level (log2 read counts): 8.23
PRPF40A Expression in NALM6 Cells: 8.23
