SLC29A2

Entrez Summary: N/A
UniProt Summary: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. {ECO:0000269|PubMed:9396714}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Nicotinate 1000μM R03 exp140	-2.15
GW501516 25μM R06 exp285	-1.94
Menadione 5μM R06 exp292	-1.94
HMS-I2 10μM R06 exp288	-1.88
Taxol 0.004μM R03 exp103	-1.74
UMK57 0.6μM R03 exp107	-1.74
Arsenate 40μM R06 exp264	-1.71
NN-Diethyl-meta-toluamide 500μM R08 exp438	1.72
Chloroquine 32μM R08 exp470	1.74
Thioridazine 5μM R08 exp530	1.79
Nicotinamide 2000μM R01 exp50	1.87

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution