TAF11
Gene Information
- Official Symbol: TAF11
- Official Name: TATA-box binding protein associated factor 11
- Aliases and Previous Symbols: N/A
- Entrez ID: 6882
- UniProt: Q15544
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively).
Pfam Domains GO Terms
Pfam Domains
| TAFII28 |
| CBFD NFYB HMF |
GO Terms
| RNA polymerase II preinitiation complex assembly |
| vitamin D receptor binding |
| positive regulation by host of viral transcription |
| transcription preinitiation complex assembly |
| thyroid hormone receptor binding |
| transcription factor TFIID complex |
| positive regulation of viral transcription |
| regulation of viral transcription |
| snRNA transcription by RNA polymerase II |
| modification by host of symbiont morphology or physiology |
| snRNA transcription |
| interaction with symbiont |
| ncRNA transcription |
| protein N-terminus binding |
| positive regulation of viral process |
| modification of morphology or physiology of other organism involved in symbiotic interaction |
| modification of morphology or physiology of other organism |
| transcription initiation from RNA polymerase II promoter |
| regulation of signal transduction by p53 class mediator |
| protein-DNA complex assembly |
| regulation of viral process |
| DNA-templated transcription, initiation |
| regulation of symbiosis, encompassing mutualism through parasitism |
| protein-DNA complex subunit organization |
| transcription coactivator activity |
| transcription factor binding |
| transcription by RNA polymerase II |
| protein heterodimerization activity |
| positive regulation of multi-organism process |
| transcription, DNA-templated |
| nucleic acid-templated transcription |
| RNA biosynthetic process |
| regulation of multi-organism process |
| symbiotic process |
| interspecies interaction between organisms |
| cellular protein-containing complex assembly |
| Golgi apparatus |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| organic cyclic compound biosynthetic process |
| DNA binding |
| protein-containing complex assembly |
| cellular nitrogen compound biosynthetic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| RNA metabolic process |
| cellular macromolecule biosynthetic process |
| positive regulation of RNA metabolic process |
| macromolecule biosynthetic process |
| regulation of intracellular signal transduction |
| protein-containing complex subunit organization |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4036
- Expression level (log2 read counts): 5.56
Expression Distribution
TAF11 Expression in NALM6 Cells: 5.56
