TEX10
Gene Information
- Official Symbol: TEX10
- Official Name: testis expressed 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 54881
- UniProt: Q9NXF1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211). {ECO:0000269|PubMed:21326211, ECO:0000269|PubMed:22872859}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1454
- Expression level (log2 read counts): 6.18
TEX10 Expression in NALM6 Cells: 6.18
