UBR4
Gene Information
- Official Symbol: UBR4
- Official Name: ubiquitin protein ligase E3 component n-recognin 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 23352
- UniProt: Q5T4S7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein. [provided by RefSeq, Aug 2010].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1574
- Expression level (log2 read counts): 8.61
UBR4 Expression in NALM6 Cells: 8.61
