UNK
Gene Information
- Official Symbol: UNK
- Official Name: unk zinc finger
- Aliases and Previous Symbols: N/A
- Entrez ID: 85451
- UniProt: Q9C0B0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280). {ECO:0000269|PubMed:25737280}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7560
- Expression level (log2 read counts): 5.77
UNK Expression in NALM6 Cells: 5.77
