GJA10

Entrez Summary: N/A
UniProt Summary: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Connexin CCC
Connexin

gap junction channel activity
detection of light stimulus involved in sensory perception
detection of light stimulus involved in visual perception
connexin complex
detection of visible light
detection of light stimulus
synapse assembly
detection of external stimulus
detection of abiotic stimulus
visual perception
sensory perception of light stimulus
synapse organization
response to light stimulus
response to radiation
detection of stimulus involved in sensory perception
detection of stimulus
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
sensory perception
multi-organism reproductive process
response to abiotic stimulus
transmembrane transport
nervous system process
reproductive process
reproduction
system process