GNL2

Gene Information
  • Official Symbol: GNL2
  • Official Name: G protein nucleolar 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 29889
  • UniProt: Q13823
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195). {ECO:0000250, ECO:0000269|PubMed:26203195}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1703
  • Expression level (log2 read counts): 7.1

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1