LCTL

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
A-366 10μM R03 exp115	-2.02
L-BMAA 500 to 750μM on day4 R04 exp185	-1.99
Bleomycin 5μM R08 exp459	-1.92
WYE-354 6μM R02 exp90	-1.82
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	-1.81
UMK57 1μM R01 exp59	1.73
Menadione 5μM R06 exp292	1.81
GW501516 25μM R06 exp285	1.86
HMS-I1 1μM R01 exp46	2.1
39°C R06 exp303	2.14

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

beta-glucosidase activity
lens morphogenesis in camera-type eye
brush border
lens development in camera-type eye
camera-type eye morphogenesis
eye morphogenesis
visual perception
sensory perception of light stimulus
sensory organ morphogenesis
camera-type eye development
eye development
visual system development
sensory system development
carbohydrate metabolic process
sensory organ development
endoplasmic reticulum membrane
animal organ morphogenesis
sensory perception
endoplasmic reticulum
nervous system process
system process