MYH3

Gene Information
  • Official Symbol: MYH3
  • Official Name: myosin heavy chain 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 4621
  • UniProt: P11055
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Muscle contraction.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7992
  • Expression level (log2 read counts): 3.34

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1