SLC35B4

Entrez Summary: N/A
UniProt Summary: Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi. {ECO:0000269|PubMed:15911612}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

TPT
UAA

UDP-xylose transmembrane transporter activity
UDP-xylose transmembrane transport
UDP-N-acetylglucosamine transmembrane transporter activity
UDP-N-acetylglucosamine transmembrane transport
pyrimidine nucleotide-sugar transmembrane transport
nucleotide-sugar transmembrane transport
regulation of gluconeogenesis
transmembrane transporter activity
integral component of Golgi membrane
carbohydrate derivative transport
carbohydrate transport
regulation of carbohydrate biosynthetic process
integral component of endoplasmic reticulum membrane
regulation of glucose metabolic process
regulation of cellular carbohydrate metabolic process
regulation of carbohydrate metabolic process
nucleobase-containing compound transport
anion transmembrane transport
regulation of small molecule metabolic process
organic anion transport
anion transport
Golgi membrane
ion transmembrane transport
Golgi apparatus
endoplasmic reticulum
transmembrane transport
ion transport
nitrogen compound transport