ADAD1

Entrez Summary: N/A
UniProt Summary: Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Cincreasin 100μM R08 exp473	-1.76
NN-Diethyl-meta-toluamide 100μM R05 exp237	-1.72
HMS-I1 1μM R01 exp46	-1.71
NMS-873 0.07μM R07 exp380	-1.71

A deamin
dsrm

tRNA-specific adenosine deaminase activity
double-stranded RNA adenosine deaminase activity
adenosine to inosine editing
base conversion or substitution editing
double-stranded RNA binding
spermatid development
spermatid differentiation
RNA modification
germ cell development
cellular process involved in reproduction in multicellular organism
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
nucleolus
RNA processing
multi-organism reproductive process
reproductive process
reproduction
cell development
RNA metabolic process
gene expression