BUD31

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 737/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	27/28
bone	26/26
breast	32/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	29/29
uterus	5/5

Expression Distribution

Gene	Correlation
PRIM1	0.529
PSMB4	0.409

positive regulation of androgen receptor activity
nuclear hormone receptor binding
U2-type catalytic step 2 spliceosome
nuclear receptor transcription coactivator activity
spliceosomal complex
nuclear chromatin
positive regulation of DNA-binding transcription factor activity
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
RNA splicing
regulation of DNA-binding transcription factor activity
mRNA processing
mRNA metabolic process
RNA processing
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
positive regulation of signal transduction
RNA metabolic process
positive regulation of RNA metabolic process
positive regulation of molecular function
positive regulation of cell communication
positive regulation of signaling
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
gene expression
positive regulation of biosynthetic process