C1QL4

Entrez Summary: N/A
UniProt Summary: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Adefovir 20μM R07 exp332	1.77
Ethanol 0.01 R05 exp234	1.79
ABT-702 5μM R07 exp318	1.89
Mubritinib 0.2μM R02 exp65	1.89
Docosahexaenoic-acid 50μM R07 exp356	2.01

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of fibroblast proliferation
negative regulation of fat cell differentiation
collagen trimer
negative regulation of ERK1 and ERK2 cascade
regulation of fibroblast proliferation
regulation of fat cell differentiation
negative regulation of MAPK cascade
regulation of ERK1 and ERK2 cascade
negative regulation of protein phosphorylation
negative regulation of phosphorylation
negative regulation of intracellular signal transduction
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
negative regulation of protein modification process
negative regulation of cell population proliferation
negative regulation of cell differentiation
regulation of MAPK cascade
negative regulation of developmental process
negative regulation of cellular protein metabolic process
identical protein binding
negative regulation of protein metabolic process
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
regulation of protein phosphorylation
regulation of phosphorylation
extracellular space
regulation of cell population proliferation
negative regulation of response to stimulus
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of cell differentiation
regulation of intracellular signal transduction
regulation of protein modification process