C1QTNF3
Gene Information
- Official Symbol: C1QTNF3
- Official Name: C1q and TNF related 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 114899
- UniProt: Q9BXJ4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| C1q |
| Collagen |
GO Terms
| positive regulation of adiponectin secretion |
| regulation of adiponectin secretion |
| negative regulation of monocyte chemotactic protein-1 production |
| cellular triglyceride homeostasis |
| negative regulation of interleukin-6 secretion |
| regulation of monocyte chemotactic protein-1 production |
| negative regulation of gluconeogenesis |
| negative regulation of chemokine production |
| negative regulation of NIK/NF-kappaB signaling |
| acylglycerol homeostasis |
| triglyceride homeostasis |
| negative regulation of cellular carbohydrate metabolic process |
| negative regulation of interleukin-6 production |
| regulation of endocrine process |
| regulation of gluconeogenesis |
| negative regulation of carbohydrate metabolic process |
| protein trimerization |
| collagen trimer |
| negative regulation of cytokine secretion |
| regulation of chemokine production |
| cell |
| negative regulation of small molecule metabolic process |
| regulation of carbohydrate biosynthetic process |
| fat cell differentiation |
| regulation of NIK/NF-kappaB signaling |
| regulation of glucose metabolic process |
| positive regulation of hormone secretion |
| negative regulation of protein secretion |
| lipid homeostasis |
| negative regulation of inflammatory response |
| positive regulation of cytokine secretion |
| regulation of cellular carbohydrate metabolic process |
| negative regulation of peptide secretion |
| regulation of interleukin-6 production |
| negative regulation of protein transport |
| negative regulation of establishment of protein localization |
| negative regulation of secretion by cell |
| regulation of cytokine secretion |
| regulation of carbohydrate metabolic process |
| negative regulation of defense response |
| negative regulation of secretion |
| regulation of hormone secretion |
| positive regulation of protein secretion |
| negative regulation of cytokine production |
| positive regulation of peptide secretion |
| regulation of inflammatory response |
| negative regulation of response to external stimulus |
| positive regulation of secretion by cell |
| positive regulation of protein transport |
| regulation of small molecule metabolic process |
| positive regulation of secretion |
| positive regulation of cytokine production |
| positive regulation of establishment of protein localization |
| regulation of protein secretion |
| negative regulation of transport |
| regulation of peptide secretion |
| negative regulation of intracellular signal transduction |
| protein complex oligomerization |
| regulation of hormone levels |
| regulation of system process |
| regulation of cytokine production |
| regulation of protein transport |
| regulation of peptide transport |
| cellular chemical homeostasis |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| molecular function |
| regulation of defense response |
| regulation of secretion |
| cellular homeostasis |
| positive regulation of transport |
| regulation of protein localization |
| regulation of response to external stimulus |
| chemical homeostasis |
| negative regulation of multicellular organismal process |
| negative regulation of signal transduction |
| negative regulation of cell communication |
| negative regulation of signaling |
| regulation of response to stress |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| protein-containing complex assembly |
| negative regulation of response to stimulus |
| homeostatic process |
| positive regulation of multicellular organismal process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| protein-containing complex subunit organization |
| regulation of transport |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Radicicol 0.16μM R05 exp242 | -2.06 |
| Quercetin 20μM R08 exp517 | 2.15 |
| Hinokiflavone 12μM R08 exp487 | 2.27 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 16603
- Expression level (log2 read counts): 2.64
Expression Distribution
C1QTNF3 Expression in NALM6 Cells: 2.64
