C2orf53

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Trimetrexate 0.03μM R08 exp535	-2.62
Betulinic acid 10 to 15μM on day4 R05 exp222	-2.34
Bisphenol F 50μM R08 exp457	-2.11
Menadione 5μM R06 exp292	-2.04
Isoniazid 100μM R08 exp494	-1.98
SNS-032 15μM R08 exp443	-1.91
UNC1999 2μM R03 exp155	-1.89
BML-284 0.09μM R08 exp460	-1.88
JQ1 0.8μM R08 exp435	-1.84
Hippuristanol 0.12μM R08 exp489 no dilution day6	-1.82
Dynasore 7μM R08 exp436	-1.81
Hinokiflavone 12μM R08 exp487	-1.75
GSK-J4 1-1.25μM to day4 R07 exp363	-1.7

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution