CAMK2G

Entrez Summary: The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gene	Correlation
KCTD5	0.411
LAMTOR4	0.409

calcium-dependent protein serine/threonine phosphatase activity
regulation of skeletal muscle adaptation
calmodulin-dependent protein kinase activity
sarcoplasmic reticulum membrane
insulin secretion
peptide hormone secretion
endocytic vesicle membrane
hormone secretion
interferon-gamma-mediated signaling pathway
regulation of cellular response to heat
hormone transport
regulation of muscle adaptation
protein secretion
establishment of protein localization to extracellular region
cellular response to interferon-gamma
protein localization to extracellular region
signal release
peptide secretion
response to interferon-gamma
calmodulin binding
protein dephosphorylation
regulation of muscle system process
regulation of calcium ion transport
dephosphorylation
neuron projection
regulation of metal ion transport
protein complex oligomerization
regulation of hormone levels
regulation of system process
cytokine-mediated signaling pathway
regulation of ion transport
regulation of cellular response to stress
innate immune response
protein homodimerization activity
defense response to other organism
protein phosphorylation
secretion by cell
cellular response to cytokine stimulus
export from cell
identical protein binding