CLASP2
Gene Information
- Official Symbol: CLASP2
- Official Name: cytoplasmic linker associated protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 23122
- UniProt: O75122
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| CLASP N |
GO Terms
| negative regulation of wound healing, spreading of epidermal cells |
| positive regulation of basement membrane assembly involved in embryonic body morphogenesis |
| regulation of basement membrane organization |
| basal cortex |
| regulation of basement membrane assembly involved in embryonic body morphogenesis |
| regulation of wound healing, spreading of epidermal cells |
| kinetochore microtubule |
| positive regulation of extracellular matrix disassembly |
| dystroglycan binding |
| exit from mitosis |
| regulation of extracellular matrix disassembly |
| negative regulation of morphogenesis of an epithelium |
| microtubule plus-end binding |
| negative regulation of focal adhesion assembly |
| microtubule nucleation |
| positive regulation of extracellular matrix organization |
| negative regulation of stress fiber assembly |
| negative regulation of adherens junction organization |
| negative regulation of cell junction assembly |
| negative regulation of actin filament bundle assembly |
| negative regulation of microtubule depolymerization |
| microtubule anchoring |
| regulation of microtubule depolymerization |
| microtubule polymerization |
| regulation of gastrulation |
| negative regulation of microtubule polymerization or depolymerization |
| positive regulation of embryonic development |
| negative regulation of cell-matrix adhesion |
| regulation of extracellular matrix organization |
| cell leading edge |
| microtubule polymerization or depolymerization |
| cytoplasmic microtubule |
| regulation of focal adhesion assembly |
| regulation of cell-substrate junction assembly |
| negative regulation of protein depolymerization |
| negative regulation of cell-substrate adhesion |
| regulation of adherens junction organization |
| negative regulation of protein complex disassembly |
| negative regulation of wound healing |
| mitotic spindle organization |
| mitotic spindle |
| regulation of stress fiber assembly |
| regulation of microtubule polymerization or depolymerization |
| regulation of epithelial to mesenchymal transition |
| regulation of protein depolymerization |
| kinetochore |
| negative regulation of response to wounding |
| protein polymerization |
| positive regulation of exocytosis |
| regulation of actomyosin structure organization |
| condensed chromosome kinetochore |
| regulation of cell junction assembly |
| vesicle targeting |
| regulation of actin filament bundle assembly |
| microtubule organizing center organization |
| ruffle membrane |
| microtubule cytoskeleton organization involved in mitosis |
| regulation of protein complex disassembly |
| regulation of cell-matrix adhesion |
| regulation of embryonic development |
| negative regulation of supramolecular fiber organization |
| Golgi organization |
| cell cortex |
| regulation of wound healing |
| negative regulation of cytoskeleton organization |
| positive regulation of epithelial cell migration |
| mitotic nuclear division |
| spindle organization |
| microtubule organizing center |
| regulation of response to wounding |
| trans-Golgi network |
| establishment of vesicle localization |
| regulation of morphogenesis of an epithelium |
| protein localization to plasma membrane |
| vesicle localization |
| regulation of microtubule cytoskeleton organization |
| establishment or maintenance of cell polarity |
| regulation of cell-substrate adhesion |
| regulation of epithelial cell migration |
| regulation of microtubule-based process |
| regulation of exocytosis |
| protein localization to cell periphery |
| microtubule binding |
| negative regulation of cell migration |
| regulation of actin filament organization |
| mitotic cell cycle phase transition |
| negative regulation of cell adhesion |
| negative regulation of cell motility |
| cell cycle phase transition |
| nuclear division |
| negative regulation of cellular component movement |
| organelle fission |
| microtubule |
| negative regulation of locomotion |
| regulation of actin cytoskeleton organization |
| regulation of supramolecular fiber organization |
| establishment of organelle localization |
| negative regulation of response to external stimulus |
| negative regulation of organelle organization |
| regulation of actin filament-based process |
| positive regulation of secretion by cell |
| focal adhesion |
| endomembrane system organization |
| positive regulation of secretion |
| supramolecular fiber organization |
| microtubule cytoskeleton organization |
| protein localization to membrane |
| cell division |
| positive regulation of cell migration |
| positive regulation of cellular component biogenesis |
| positive regulation of cell motility |
| positive regulation of cellular component movement |
| regulation of cytoskeleton organization |
| regulation of vesicle-mediated transport |
| positive regulation of locomotion |
| organelle localization |
| mitotic cell cycle process |
| microtubule-based process |
| regulation of cell adhesion |
| mitotic cell cycle |
| negative regulation of cellular component organization |
| regulation of secretion by cell |
| regulation of secretion |
| cellular protein-containing complex assembly |
| regulation of cell migration |
| regulation of cell motility |
| negative regulation of developmental process |
| regulation of cellular component biogenesis |
| regulation of locomotion |
| Golgi apparatus |
| positive regulation of transport |
| regulation of cellular component movement |
| cell cycle process |
| regulation of anatomical structure morphogenesis |
| regulation of response to external stimulus |
| cytoskeleton organization |
| positive regulation of cellular component organization |
| regulation of organelle organization |
| cell cycle |
| positive regulation of developmental process |
| regulation of response to stress |
| protein-containing complex assembly |
| cellular protein localization |
| cellular macromolecule localization |
| negative regulation of response to stimulus |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
| establishment of localization in cell |
| protein-containing complex subunit organization |
| regulation of transport |
| vesicle-mediated transport |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A
| Tissue | Fraction Of Cell Lines Where Essential |
|---|
Essentiality in NALM6
- Essentiality Rank: 16263
- Expression level (log2 read counts): 7.1
Expression Distribution
CLASP2 Expression in NALM6 Cells: 7.1
