CREBRF

Gene Information

Official Symbol: CREBRF
Official Name: CREB3 regulatory factor
Aliases and Previous Symbols: N/A
Entrez ID: 153222
UniProt: Q8IUR6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 3880
Expression level (log2 read counts): 3.68

Expression Distribution

Screen	Score
Ethambutol 25μM R08 exp481	1.7
Resveratrol 16μM R03 exp147	1.76

negative regulation of glucocorticoid mediated signaling pathway
regulation of prolactin signaling pathway
positive regulation of prolactin signaling pathway
regulation of glucocorticoid mediated signaling pathway
maternal behavior
parental behavior
reproductive behavior
positive regulation of cytokine-mediated signaling pathway
positive regulation of response to cytokine stimulus
endoplasmic reticulum unfolded protein response
cellular response to unfolded protein
cellular response to topologically incorrect protein
response to unfolded protein
regulation of cytokine-mediated signaling pathway
regulation of response to cytokine stimulus
response to topologically incorrect protein
response to endoplasmic reticulum stress
nuclear body
RNA polymerase II regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
behavior
multicellular organismal reproductive process
multicellular organism reproduction
positive regulation of transcription by RNA polymerase II
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
reproductive process
reproduction
positive regulation of transcription, DNA-templated
DNA-binding transcription factor activity, RNA polymerase II-specific
negative regulation of response to stimulus
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
positive regulation of signal transduction
cellular response to stress
positive regulation of RNA metabolic process
positive regulation of cell communication
positive regulation of signaling
positive regulation of nucleobase-containing compound metabolic process