EPC2

Entrez Summary: N/A
UniProt Summary: May play a role in transcription or DNA repair. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 36/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	2/28
bone	6/25
breast	0/33
central nervous system	4/56
cervix	0/4
colorectal	0/17
esophagus	1/13
fibroblast	0/1
gastric	1/15
kidney	1/21
liver	0/20
lung	7/75
lymphocyte	0/14
ovary	0/26
pancreas	1/24
peripheral nervous system	3/16
plasma cell	0/15
prostate	0/1
skin	2/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution

Gene	Correlation
HARS	0.523
EPC1	0.479

E Pc C
EPL1

Piccolo NuA4 histone acetyltransferase complex
histone acetyltransferase activity
histone acetylation
internal peptidyl-lysine acetylation
peptidyl-lysine acetylation
internal protein amino acid acetylation
protein acetylation
protein acylation
peptidyl-lysine modification
histone modification
covalent chromatin modification
DNA repair
chromatin organization
DNA metabolic process
cellular response to DNA damage stimulus
peptidyl-amino acid modification
chromosome organization
cellular response to stress