ERMAP

Official Symbol: ERMAP
Official Name: erythroblast membrane associated protein (Scianna blood group)
Aliases and Previous Symbols: N/A
Entrez ID: 114625
UniProt: Q96PL5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record represents the ERMAP*001.1.1 allele.
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

V-set
SPRY

T cell receptor signaling pathway
antigen receptor-mediated signaling pathway
signaling receptor binding
external side of plasma membrane
immune response-activating cell surface receptor signaling pathway
immune response-regulating cell surface receptor signaling pathway
immune response-activating signal transduction
immune response-regulating signaling pathway
activation of immune response
positive regulation of immune response
regulation of immune response
positive regulation of immune system process
regulation of immune system process