FAM96A

Entrez Summary: N/A
UniProt Summary: May play a role in chromosome segregation through establishment of sister chromatid cohesion. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
2-Methoxyestradiol 0.2μM R01 exp40	-1.93
NN-Dimethylsphingosine 2.5μM R08 exp508	-1.82
42°C R08 exp539	-1.74
CB-839 10μM R05 exp224	-1.73
Isoniazid 100μM R08 exp494	2.13

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

protein maturation by [4Fe-4S] cluster transfer
CIA complex
protein maturation by iron-sulfur cluster transfer
iron-sulfur cluster assembly
metallo-sulfur cluster assembly
cofactor biosynthetic process
protein maturation
chromosome segregation
sulfur compound metabolic process
cofactor metabolic process
gene expression