FILIP1

Gene Information
  • Official Symbol: FILIP1
  • Official Name: filamin A interacting protein 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 27145
  • UniProt: Q7Z7B0
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016].
  • UniProt Summary: By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A. {ECO:0000250|UniProtKB:Q8K4T4}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8366
  • Expression level (log2 read counts): 1.55

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1