G3BP2

Entrez Summary: N/A
UniProt Summary: Probable scaffold protein that may be involved in mRNA transport. {ECO:0000305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

NTF2
RRM 1

positive regulation of stress granule assembly
regulation of stress granule assembly
cytoplasmic sequestering of NF-kappaB
stress granule assembly
cytoplasmic sequestering of transcription factor
receptor signaling complex adaptor activity
cytoplasmic sequestering of protein
cytoplasmic stress granule
positive regulation of organelle assembly
negative regulation of NF-kappaB transcription factor activity
maintenance of protein location
mRNA transport
ribonucleoprotein complex
negative regulation of DNA-binding transcription factor activity
mRNA binding
maintenance of location
nucleic acid transport
RNA transport
establishment of RNA localization
RNA localization
regulation of organelle assembly
ribonucleoprotein complex assembly
nucleobase-containing compound transport
ribonucleoprotein complex subunit organization
Ras protein signal transduction
positive regulation of protein complex assembly
small GTPase mediated signal transduction
protein homooligomerization
regulation of DNA-binding transcription factor activity
regulation of protein complex assembly
ribonucleoprotein complex biogenesis
protein complex oligomerization
positive regulation of cellular component biogenesis
positive regulation of organelle organization
viral process
organelle assembly
innate immune response
symbiotic process
interspecies interaction between organisms
cellular protein-containing complex assembly