HAPLN4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Lapatinib 5μM R01 exp47	-2.35
Nifuroxazide 1μM R01 exp51	-1.8
Ribavirin 10μM R01 exp52	-1.72
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	1.74
Erlotinib 10μM R05 exp216	1.76
Taxol 0.004μM R03 exp103	1.85

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Xlink
V-set

hyaluronic acid binding
extracellular matrix
skeletal system development
cell adhesion
biological adhesion
central nervous system development