HAUS5

Entrez Summary: N/A
UniProt Summary: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 716/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	27/28
blood	27/28
bone	25/26
breast	31/33
central nervous system	55/56
cervix	4/4
colorectal	15/17
esophagus	12/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	24/26
pancreas	23/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	23/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	28/29
uterus	4/5

Expression Distribution

HAUS complex
centrosome cycle
microtubule organizing center organization
ciliary basal body-plasma membrane docking
spindle assembly
spindle
G2/M transition of mitotic cell cycle
cell cycle G2/M phase transition
spindle organization
organelle localization by membrane tethering
membrane docking
regulation of G2/M transition of mitotic cell cycle
regulation of cell cycle G2/M phase transition
mitotic cell cycle phase transition
cell cycle phase transition
microtubule
cilium assembly
cilium organization
regulation of mitotic cell cycle phase transition
plasma membrane bounded cell projection assembly
regulation of cell cycle phase transition
cell projection assembly
microtubule cytoskeleton organization
centrosome
cell division
organelle localization
mitotic cell cycle process
regulation of mitotic cell cycle
microtubule-based process
mitotic cell cycle
regulation of cell cycle process
organelle assembly
molecular function
cell cycle process
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
regulation of cell cycle
cell cycle