KIF13B

Entrez Summary: N/A
UniProt Summary: Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes. {ECO:0000269|PubMed:20194617}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

paranode region of axon
14-3-3 protein binding
kinesin complex
microvillus
microtubule motor activity
regulation of axonogenesis
T cell activation
ATPase activity
microtubule binding
microtubule-based movement
axon
regulation of cell morphogenesis involved in differentiation
microtubule
protein targeting
lymphocyte activation
protein kinase binding
regulation of cell morphogenesis
regulation of neuron projection development
regulation of neuron differentiation
microtubule-based process
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
regulation of nervous system development
leukocyte activation
regulation of cell development
intracellular protein transport
regulation of anatomical structure morphogenesis
cell activation
ATP binding
protein transport
intracellular transport
generation of neurons
peptide transport
movement of cell or subcellular component
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
neurogenesis