KLHDC3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Kelch 2
Kelch 1

reciprocal meiotic recombination
homologous recombination
IRE1-mediated unfolded protein response
endoplasmic reticulum unfolded protein response
meiosis I
meiosis I cell cycle process
cellular response to unfolded protein
cellular response to topologically incorrect protein
meiotic nuclear division
response to unfolded protein
meiotic cell cycle process
response to topologically incorrect protein
DNA recombination
meiotic cell cycle
nuclear chromatin
response to endoplasmic reticulum stress
nuclear division
organelle fission
chromatin binding
DNA metabolic process
cell cycle process
cell cycle
reproductive process
reproduction
cellular response to stress