LGI4

Entrez Summary: N/A
UniProt Summary: Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation (By similarity). {ECO:0000250|UniProtKB:Q8K1S1}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glial cell proliferation
peripheral nervous system axon ensheathment
myelination in peripheral nervous system
Schwann cell development
Schwann cell differentiation
neuron maturation
regulation of myelination
peripheral nervous system development
adult locomotory behavior
myelination
glial cell development
axon ensheathment
ensheathment of neurons
anatomical structure maturation
adult behavior
cell maturation
glial cell differentiation
locomotory behavior
gliogenesis
developmental maturation
cell population proliferation
behavior
neuron development
regulation of nervous system development
neuron differentiation
generation of neurons
extracellular space
neurogenesis
cell development
extracellular region