MDH1B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
WNT3A 44ng/ml R08 exp537	1.85
2-Methoxyestradiol 0.2μM R01 exp40	2.08

L-malate dehydrogenase activity
malate metabolic process
oxaloacetate metabolic process
tricarboxylic acid cycle
NADH metabolic process
aerobic respiration
dicarboxylic acid metabolic process
cellular respiration
energy derivation by oxidation of organic compounds
generation of precursor metabolites and energy
carbohydrate metabolic process
carboxylic acid metabolic process
oxidation-reduction process
oxoacid metabolic process
organic acid metabolic process
small molecule metabolic process