MED11

Gene Information
  • Official Symbol: MED11
  • Official Name: mediator complex subunit 11
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 400569
  • UniProt: Q9P086
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1040
  • Expression level (log2 read counts): 3.9

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1