MOB4

Entrez Summary: N/A
UniProt Summary: May play a role in membrane trafficking, specifically in membrane budding reactions. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Brefeldin A 0.02μM R00 exp8	-1.84
Chloroquine 32μM R08 exp470	-1.83
BI-2536 0.0042μM R03 exp95	-1.8
Betulinic acid 10 to 15μM on day4 R05 exp222	-1.75
UNC1999 2μM R03 exp155	-1.73
Arsenate 40μM R06 exp264	-1.7
Senexin-A 25μM R07 exp400	-1.7
Rotenone 20μM R00 exp34	1.78
Docetaxel 0.002μM R01 exp45	2.39

Global Fraction of Cell Lines Where Essential: 52/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	3/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	4/56
cervix	0/4
colorectal	0/17
esophagus	1/13
fibroblast	0/1
gastric	1/16
kidney	1/21
liver	2/20
lung	4/75
lymphocyte	0/16
ovary	8/26
pancreas	2/24
peripheral nervous system	0/16
plasma cell	1/15
prostate	0/1
skin	2/24
soft tissue	3/9
thyroid	1/2
upper aerodigestive	1/22
urinary tract	5/29
uterus	0/5

Expression Distribution

Golgi cisterna membrane
perinuclear region of cytoplasm
Golgi apparatus