MYOF

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
UMK57 1μM R01 exp59	-1.7
UM0129480 7μM R02 exp85	1.76
Deguelin 0.05μM R02 exp69	1.8
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.89

T-tubule organization
plasma membrane repair
glycerol metabolic process
myoblast fusion
alditol metabolic process
regulation of vascular endothelial growth factor receptor signaling pathway
syncytium formation by plasma membrane fusion
cell-cell fusion
syncytium formation
myotube differentiation
muscle fiber development
cellular response to heat
caveola
plasma membrane organization
phospholipid binding
response to heat
polyol metabolic process
striated muscle cell development
cytoplasmic vesicle membrane
muscle cell development
cellular carbohydrate metabolic process
response to temperature stimulus
nuclear envelope
striated muscle cell differentiation
nuclear membrane
muscle cell differentiation
muscle contraction
cytoplasmic vesicle
regulation of cellular response to growth factor stimulus
muscle system process
alcohol metabolic process
blood circulation
circulatory system process
endomembrane system organization
organic hydroxy compound metabolic process
carbohydrate metabolic process
muscle structure development
wound healing
response to wounding
intracellular membrane-bounded organelle