NAP1L2

Entrez Summary: The protein encoded by this intronless gene is a member of the nucleosome assembly protein (NAP) family. The encoded protein represents a class of tissue-specific factors that interact with chromatin to regulate neuronal cell proliferation. [provided by RefSeq, Jan 2011].
UniProt Summary: Acidic protein which may be involved in interactions with other proteins or DNA. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/683

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/25
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/14
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

positive regulation of histone H3-K14 acetylation
regulation of histone H3-K14 acetylation
positive regulation of histone H3-K9 acetylation
regulation of stem cell division
regulation of histone H3-K9 acetylation
positive regulation of histone acetylation
positive regulation of peptidyl-lysine acetylation
positive regulation of protein acetylation
regulation of histone acetylation
regulation of peptidyl-lysine acetylation
regulation of protein acetylation
positive regulation of histone modification
positive regulation of chromatin organization
nucleosome assembly
histone binding
chromatin assembly
regulation of histone modification
chromatin assembly or disassembly
nucleosome organization
regulation of cell division
positive regulation of chromosome organization
DNA packaging
regulation of chromatin organization
protein-DNA complex assembly
protein-DNA complex subunit organization
DNA conformation change
regulation of chromosome organization
positive regulation of neuron differentiation
chromatin binding
positive regulation of neurogenesis
positive regulation of nervous system development
positive regulation of cell development
positive regulation of organelle organization
regulation of neuron differentiation
chromatin organization
regulation of neurogenesis
cellular protein-containing complex assembly
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation