NID1

Entrez Summary: This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. [provided by RefSeq, Jul 2008].
UniProt Summary: Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

laminin-1 binding
glomerular basement membrane development
proteoglycan binding
basement membrane organization
laminin binding
cell periphery
glomerulus development
collagen binding
basement membrane
positive regulation of cell-substrate adhesion
nephron development
cell-matrix adhesion
extracellular matrix structural constituent
cell-substrate adhesion
regulation of cell-substrate adhesion
kidney development
renal system development
urogenital system development
extracellular matrix organization
collagen-containing extracellular matrix
extracellular structure organization
positive regulation of cell adhesion
regulation of cell adhesion
calcium ion binding
cell adhesion
biological adhesion
extracellular region