NLGN4Y

Entrez Summary: This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011].
UniProt Summary: Putative neuronal cell surface protein involved in cell- cell-interactions.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

Screen	Score
Docetaxel 0.002μM R01 exp45	-1.75
Pimelic-diphenylamide-106 0.5μM R00 exp27	1.77

Abhydrolase 3
COesterase

symmetric, GABA-ergic, inhibitory synapse
asymmetric, glutamatergic, excitatory synapse
spanning component of membrane
presynaptic membrane assembly
presynaptic membrane organization
postsynaptic membrane assembly
neurexin family protein binding
neuron cell-cell adhesion
vocalization behavior
presynapse assembly
postsynapse assembly
presynapse organization
postsynaptic membrane organization
membrane assembly
membrane biogenesis
synaptic vesicle endocytosis
presynaptic endocytosis
intraspecies interaction between organisms
synaptic vesicle recycling
social behavior
cell adhesion molecule binding
scaffold protein binding
multi-organism behavior
postsynapse organization
synapse assembly
presynapse
synaptic vesicle cycle
vesicle-mediated transport in synapse
learning
postsynaptic membrane
signaling receptor activity
postsynaptic density
learning or memory
synapse
synapse organization
cognition
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
cell-cell adhesion
cell junction