NOBOX
Gene Information
- Official Symbol: NOBOX
- Official Name: NOBOX oogenesis homeobox
- Aliases and Previous Symbols: N/A
- Entrez ID: 135935
- UniProt: O60393
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.[provided by RefSeq, May 2011].
- UniProt Summary: Transcription factor which may play a role in oogenesis. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG- 3' and 5'-TAATTA-3'. {ECO:0000269|PubMed:25514101, ECO:0000269|PubMed:27798098}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 4039
- Expression level (log2 read counts): -7.68