PHF14

Gene Information

Official Symbol: PHF14
Official Name: PHD finger protein 14
Aliases and Previous Symbols: N/A
Entrez ID: 9678
UniProt: O94880
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Docosahexaenoic-acid 50μM R07 exp356	-1.95
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-1.71
BI-D1870 3.15μM R02 exp66	1.76
GSK626616 14μM R08 exp485	1.83
SB743921 0.001μM R05 exp244	2.36
Rotenone 2μM R00 exp33	2.39
Dimethyloxaloylglycine 100μM R05 exp229	2.7
I-BRD9 4μM R07 exp365	3.21

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 17807
Expression level (log2 read counts): 6.67

Expression Distribution

regulation of mesenchymal cell proliferation involved in lung development
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
negative regulation of mesenchymal cell proliferation involved in lung development
regulation of platelet-derived growth factor receptor-alpha signaling pathway
negative regulation of mesenchymal cell proliferation
negative regulation of platelet-derived growth factor receptor signaling pathway
regulation of platelet-derived growth factor receptor signaling pathway
regulation of mesenchymal cell proliferation
lung alveolus development
lung development
respiratory tube development
respiratory system development
negative regulation of cell population proliferation
tube development
negative regulation of transcription by RNA polymerase II
negative regulation of developmental process
negative regulation of transcription, DNA-templated
negative regulation of multicellular organismal process
negative regulation of nucleic acid-templated transcription
negative regulation of RNA biosynthetic process
negative regulation of signal transduction
negative regulation of RNA metabolic process
negative regulation of cell communication
negative regulation of signaling
negative regulation of cellular macromolecule biosynthetic process
negative regulation of nucleobase-containing compound metabolic process
negative regulation of macromolecule biosynthetic process
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
regulation of cell population proliferation
negative regulation of response to stimulus
negative regulation of gene expression