PPP1R7

Entrez Summary: N/A
UniProt Summary: Regulatory subunit of protein phosphatase 1. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Doxorubicin 0.02μM R08 exp478	-2.1
Radicicol 0.16μM R05 exp242	-1.84
ML-792 0.2μM R08 exp505	1.73
UM131593 0.2μM R03 exp106	1.75
Calcipotriol 5μM R08 exp464	1.78
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	1.99
UMK57 1μM R01 exp59	2.05

Global Fraction of Cell Lines Where Essential: 254/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	10/28
blood	9/28
bone	10/26
breast	15/33
central nervous system	24/56
cervix	1/4
colorectal	6/17
esophagus	6/13
fibroblast	1/1
gastric	4/16
kidney	10/21
liver	10/20
lung	23/75
lymphocyte	1/16
ovary	12/26
pancreas	9/24
peripheral nervous system	7/16
plasma cell	3/15
prostate	0/1
skin	10/24
soft tissue	0/9
thyroid	1/2
upper aerodigestive	11/22
urinary tract	7/29
uterus	2/5

Expression Distribution

enzyme regulator activity
protein phosphatase regulator activity
positive regulation of protein dephosphorylation
positive regulation of dephosphorylation
regulation of phosphoprotein phosphatase activity
chromosome
regulation of protein dephosphorylation
regulation of phosphatase activity
regulation of dephosphorylation
positive regulation of phosphate metabolic process
positive regulation of phosphorus metabolic process
positive regulation of protein modification process
regulation of hydrolase activity
positive regulation of cellular protein metabolic process
positive regulation of protein metabolic process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of protein modification process